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Reciprocal regulation of TORC signaling and tRNA modifications by Elongator enforces nutrient-dependent cell fate

Nutrient availability has a profound impact on cell fate. Upon nitrogen starvation, wild-type fission yeast cells uncouple cell growth from cell division to generate small, round-shaped cells that are competent for sexual differentiation. The TORC1 (TOR complex 1) and TORC2 complexes exert opposite...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Candiracci, Julie, Migeot, Valerie, Chionh, Yok-Hian, Bauer, Fanelie, Brochier, Thomas, Russell, Brandon, Shiozaki, Kazuhiro, Dedon, Peter, Hermand, Damien
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584457/
https://ncbi.nlm.nih.gov/pubmed/31223645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav0184
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