Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma

IMPORTANCE: Identification of patients with hereditary renal cell carcinoma (RCC) is important for cancer screening and, in patients with advanced disease, for guiding treatment. The prevalence of cancer-related germline mutations in patients with advanced RCC and the phenotypes associated with some...

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Publicat a:JAMA Oncol
Autors principals: Carlo, Maria I., Mukherjee, Semanti, Mandelker, Diana, Vijai, Joseph, Kemel, Yelena, Zhang, Liying, Knezevic, Andrea, Patil, Sujata, Ceyhan-Birsoy, Ozge, Huang, Kuo-Cheng, Redzematovic, Almedina, Coskey, Devyn T., Stewart, Carolyn, Pradhan, Nisha, Arnold, Angela G., Hakimi, A. Ari, Chen, Ying-Bei, Coleman, Jonathan A., Hyman, David M., Ladanyi, Marc, Cadoo, Karen A., Walsh, Michael F., Stadler, Zsofia K., Lee, Chung-Han, Feldman, Darren R., Voss, Martin H., Robson, Mark, Motzer, Robert J., Offit, Kenneth
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2018
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584283/
https://ncbi.nlm.nih.gov/pubmed/29978187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.1986
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