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Pharmacology, Pharmacokinetics and Pharmacodynamics of Eculizumab, and Possibilities for an Individualized Approach to Eculizumab

Eculizumab is the first drug approved for the treatment of complement-mediated diseases, and current dosage schedules result in large interindividual drug concentrations. This review provides insight into the pharmacokinetic and pharmacodynamic properties of eculizumab, both for reported on-label (p...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Clin Pharmacokinet
मुख्य लेखकों: Wijnsma, Kioa Lente, ter Heine, Rob, Moes, Dirk Jan A. R., Langemeijer, Saskia, Schols, Saskia E. M., Volokhina, Elena. B., van den Heuvel, Lambertus P., Wetzels, Jack F. M., van de Kar, Nicole C. A. J., Brüggemann, Roger J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer International Publishing 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584251/
https://ncbi.nlm.nih.gov/pubmed/30758736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00742-8
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