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Induced pluripotent stem cells in disease modelling and drug discovery

The derivation of induced pluripotent stem cells (iPSCs) over a decade ago sparked widespread enthusiasm for the development of new models of human disease, enhanced platforms for drug discovery, and more widespread use of autologous cell-based therapy. Early studies using directed differentiation o...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Rev Genet
Hauptverfasser: Rowe, R. Grant, Daley, George Q.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584039/
https://ncbi.nlm.nih.gov/pubmed/30737492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41576-019-0100-z
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