Neutrophils from ANCA-associated vasculitis patients show an increased capacity to activate the complement system via the alternative pathway after ANCA stimulation

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV), including granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), are autoimmune conditions associated with small vessel inflammation. Earlier studies indicate that complement activation via the alternative...

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Udgivet i:PLoS One
Main Authors: Ohlsson, Sophie, Holm, Lisa, Hansson, Christina, Ohlsson, Susanne M., Gunnarsson, Lena, Pettersson, Åsa, Skattum, Lillemor
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583988/
https://ncbi.nlm.nih.gov/pubmed/31216309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218272
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