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Association of a Novel Diagnostic Biomarker, the Plasma Cardiac Bridging Integrator 1 Score, With Heart Failure With Preserved Ejection Fraction and Cardiovascular Hospitalization

IMPORTANCE: Transverse tubule remodeling is a hallmark of heart failure. Cardiac bridging integrator 1 (cBIN1) is a circulating membrane scaffolding protein that is essential for transverse tubule health, and its plasma level declines with disease. OBJECTIVE: To determine if a cBIN1-derived score ca...

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Detalhes bibliográficos
Publicado no:JAMA Cardiol
Main Authors: Nikolova, Andriana P., Hitzeman, Tara C., Baum, Rachel, Caldaruse, Ana-Maria, Agvanian, Sosse, Xie, Yu, Geft, Dael R., Chang, David H., Moriguchi, Jaime D., Hage, Antoine, Azarbal, Babak, Czer, Lawrence S., Kittleson, Michelle M., Patel, Jignesh K., Wu, Alan H. B., Kobashigawa, Jon A., Hamilton, Michele, Hong, TingTing, Shaw, Robin M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583707/
https://ncbi.nlm.nih.gov/pubmed/30383171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2018.3539
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