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Supervised learning to quantify amyloidosis in whole brains of an Alzheimer’s disease mouse model acquired with optical projection tomography
Alzheimer’s disease (AD) is characterized by amyloidosis of brain tissues. This phenomenon is studied with genetically-modified mouse models. We propose a method to quantify amyloidosis in whole 5xFAD mouse brains, a model of AD. We use optical projection tomography (OPT) and a random forest voxel c...
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| Pubblicato in: | Biomed Opt Express |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Optical Society of America
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6583328/ https://ncbi.nlm.nih.gov/pubmed/31259073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.10.003041 |
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