Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis: The J-DAVID Randomized Clinical Trial

IMPORTANCE: Patients with chronic kidney disease have impaired vitamin D activation and elevated cardiovascular risk. Observational studies in patients treated with hemodialysis showed that the use of active vitamin D sterols was associated with lower risk of all-cause mortality, regardless of parat...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Shoji, Tetsuo, Inaba, Masaaki, Fukagawa, Masafumi, Ando, Ryoichi, Emoto, Masanori, Fujii, Hisako, Fujimori, Akira, Fukui, Mitsuru, Hase, Hiroki, Hashimoto, Tetsuya, Hirakata, Hideki, Honda, Hirokazu, Hosoya, Tatsuo, Ikari, Yuji, Inaguma, Daijo, Inoue, Toru, Isaka, Yoshitaka, Iseki, Kunitoshi, Ishimura, Eiji, Itami, Noritomo, Ito, Chiharu, Kakuta, Toshitaka, Kawai, Toru, Kawanishi, Hideki, Kobayashi, Shuzo, Kumagai, Junko, Maekawa, Kiyoshi, Masakane, Ikuto, Minakuchi, Jun, Mitsuiki, Koji, Mizuguchi, Takashi, Morimoto, Satoshi, Murohara, Toyoaki, Nakatani, Tatsuya, Negi, Shigeo, Nishi, Shinichi, Nishikawa, Mitsushige, Ogawa, Tetsuya, Ohta, Kazumichi, Ohtake, Takayasu, Okamura, Mikio, Okuno, Senji, Shigematsu, Takashi, Sugimoto, Toshitsugu, Suzuki, Masashi, Tahara, Hideki, Takemoto, Yoshiaki, Tanaka, Kenji, Tominaga, Yoshihiro, Tsubakihara, Yoshiharu, Tsujimoto, Yoshihiro, Tsuruya, Kazuhiko, Ueda, Shinichiro, Watanabe, Yuzo, Yamagata, Kunihiro, Yamakawa, Tomoyuki, Yano, Shozo, Yokoyama, Keitaro, Yorioka, Noriaki, Yoshiyama, Minoru, Nishizawa, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583075/
https://ncbi.nlm.nih.gov/pubmed/30535217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.17749
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