FCGR3A and FCGR2A Genotypes Differentially Impact Allograft Rejection and Patients' Survival After Lung Transplant

Fc gamma receptors (FcγRs) play a major role in the regulation of humoral immune responses. Single-nucleotide polymorphisms (SNPs) of FCGR2A and FCGR3A can impact the expression level, IgG affinity and function of the CD32 and CD16 FcγRs in response to their engagement by the Fc fragment of IgG. The...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Paul, Pascale, Pedini, Pascal, Lyonnet, Luc, Di Cristofaro, Julie, Loundou, Anderson, Pelardy, Mathieu, Basire, Agnes, Dignat-George, Françoise, Chiaroni, Jacques, Thomas, Pascal, Reynaud-Gaubert, Martine, Picard, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582937/
https://ncbi.nlm.nih.gov/pubmed/31249568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01208
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