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Potent and selective in vitro and in vivo antiproliferative effects of metal–organic trefoil knots

A set of metal–organic trefoil knots (M-TKs) generated by metal-templated self-assembly of a simple pair of chelating ligands were well tolerated in vitro by non-cancer cells but were significantly more potent than cisplatin in both human cancer cells––including those resistant to cisplatin––and in...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Benyettou, Farah, Prakasam, Thirumurugan, Ramdas Nair, Anjana, Witzel, Ini-Isabee, Alhashimi, Marwa, Skorjanc, Tina, Olsen, John-Carl, Sadler, Kirsten C., Trabolsi, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582759/
https://ncbi.nlm.nih.gov/pubmed/31360392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc01218d
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