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Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer

BACKGROUND: The human epidermal growth factor receptor (HER) family of transmembrane tyrosine kinases is overexpressed and correlates with poor prognosis and decreased survival in many cancers. The receptor family has been therapeutically targeted, yet tyrosine kinase inhibitors (TKIs) do not inhibi...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Maisel, Sabrina A., Broka, Derrick, Atwell, Benjamin, Bunch, Thomas, Kupp, Robert, Singh, Shiv K., Mehta, Shwetal, Schroeder, Joyce
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582486/
https://ncbi.nlm.nih.gov/pubmed/31215437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1939-7
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