Transcriptome Responses to Dexamethasone Depending on Dose and Glucocorticoid Receptor Sensitivity in the Liver

Tissue sensitivity to glucocorticoids is a key factor dictating outcome of their homeostatic and therapeutic action, whereby liver represents one of the major peripheral targets. Here, we used pigs carrying a natural gain-of-function glucocorticoid receptor (GR) variant Ala610Val (GR(Ala610Val)) as...

Full description

Saved in:
Bibliographic Details
Published in:Front Genet
Main Authors: Murani, Eduard, Trakooljul, Nares, Hadlich, Frieder, Ponsuksili, Siriluck, Wimmers, Klaus
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582245/
https://ncbi.nlm.nih.gov/pubmed/31249595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00559
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items