Development of a Rhinovirus Inoculum Using a Reverse Genetics Approach

BACKGROUND: Experimental inoculation is an important tool for common cold and asthma research. Producing rhinovirus (RV) inocula from nasal secretions has required prolonged observation of the virus donor to exclude extraneous pathogens. We produced a RV-A16 inoculum using reverse genetics and deter...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Gern, James E, Lee, Wai Ming, Swenson, Cheri A, Nakagome, Kazuyuki, Lee, Iris, Wolff, Michele, Grindle, Kristine, Sigelman, Steven, Liggett, Stephen B, Togias, Alkis, Evans, Michael, Denlinger, Loren, Gangnon, Ronald, Bochkov, Yury A, Crisafi, Gina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581892/
https://ncbi.nlm.nih.gov/pubmed/30383246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy629
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