Gradual in vitro Evolution of Cefepime Resistance in an ST131 Escherichia coli Strain Expressing a Plasmid-Encoded CMY-2 β-Lactamase

BACKGROUND: In a previous report, a clinical ST131 Escherichia coli isolate (Ec-1),producing a plasmid-encoded AmpC β-lactamase CMY-2, evolved in vivo under cefepime (FEP) treatment to the FEP-resistant Ec-2 strain expressing an extended-spectrum β-lactamase CMY-33. To compare factors responsible fo...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Main Authors: Donà, Valentina, Scheidegger, Maximilian, Pires, João, Furrer, Hansjakob, Atkinson, Andrew, Babouee Flury, Baharak
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581752/
https://ncbi.nlm.nih.gov/pubmed/31244817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01311
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