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RNAi-based functional selection identifies novel cell migration determinants dependent on PI3K and AKT pathways
Lentiviral short hairpin RNA (shRNA)-mediated genetic screening is a powerful tool for identifying loss-of-function phenotype in mammalian cells. Here, we report the identification of 91 cell migration-regulating genes using unbiased genome-wide functional genetic selection. Individual knockdown or...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6581447/ https://ncbi.nlm.nih.gov/pubmed/25347953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6217 |
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