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The synthesis of the isomeric 2′-deoxypseudouridines

Reaction of 3,4-isopropylidene-2-deoxyribose with 2,4-dit-butoxy-5-lithiopyrimidine gives the protected allo- and altro-polyols (I). Cyclisation by 5′ -tosylation then treatment with methoxide affords respectively the protected β and α-pyranosyl nucleosides (II). Mild acid treatment of allo- and alt...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Brown, D.M., Bridges, S.D., Ogden, R.C., Conrad, R.P.L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1978
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581392/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/1.suppl_1.s121
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