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Integrative network and brain expression analysis reveals mechanistic modules in ataxia

BACKGROUND: Genetic forms of ataxia are a heterogenous group of degenerative diseases of the cerebellum. Many causative genes have been identified. We aimed to systematically investigate these genes to better understand ataxia pathophysiology. METHODS: A manually curated catalogue of 71 genes involv...

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Detalhes bibliográficos
Publicado no:J Med Genet
Main Authors: Eidhof, Ilse, van de Warrenburg, Bart P, Schenck, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581079/
https://ncbi.nlm.nih.gov/pubmed/30591515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2018-105703
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