Taurine supplementation for prevention of stroke-like episodes in MELAS: a multicentre, open-label, 52-week phase III trial

OBJECTIVE: The aim of this study was to evaluate the efficacy and safety of high-dose taurine supplementation for prevention of stroke-like episodes of MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes), a rare genetic disorder caused by point mutations in the m...

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Detalhes bibliográficos
Publicado no:J Neurol Neurosurg Psychiatry
Main Authors: Ohsawa, Yutaka, Hagiwara, Hiroki, Nishimatsu, Shin-ichiro, Hirakawa, Akihiro, Kamimura, Naomi, Ohtsubo, Hideaki, Fukai, Yuta, Murakami, Tatsufumi, Koga, Yasutoshi, Goto, Yu-ichi, Ohta, Shigeo, Sunada, Yoshihide
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Neurogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581075/
https://ncbi.nlm.nih.gov/pubmed/29666206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2018-317964
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