Subclinical Cytomegalovirus DNA Is Associated with CD4 T Cell Activation and Impaired CD8 T Cell CD107a Expression in People Living with HIV despite Early Antiretroviral Therapy

Most people living with HIV (PLWH) are coinfected with cytomegalovirus (CMV). Subclinical CMV replication is associated with immune dysfunction and with increased HIV DNA in antiretroviral therapy (ART)-naive and -suppressed PLWH. To identify immunological mechanisms by which CMV could favor HIV per...

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Udgivet i:J Virol
Main Authors: Christensen-Quick, Aaron, Massanella, Marta, Frick, Andrew, Rawlings, Stephen A., Spina, Celsa, Vargas-Meneses, Milenka, Schrier, Rachel, Nakazawa, Masato, Anderson, Christy, Gianella, Sara
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580967/
https://ncbi.nlm.nih.gov/pubmed/31019052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00179-19
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