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Antagonizing the Glucocorticoid Receptor Impairs Explant-Induced Reactivation in Mice Latently Infected with Herpes Simplex Virus 1

Herpes simplex virus 1 (HSV-1) establishes lifelong latent infections in neurons. Reactivation from latency can lead to serious recurrent disease, including stromal keratitis, corneal scarring, blindness, and encephalitis. Although numerous studies link stress to an increase in the incidence of reac...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Harrison, Kelly S., Zhu, Liqian, Thunuguntla, Prasanth, Jones, Clinton
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580953/
https://ncbi.nlm.nih.gov/pubmed/30971470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00418-19
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