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Dendrigraft of Poly-l-lysine as a Promising Candidate To Reverse Heparin-based Anticoagulants in Clinical Settings

[Image: see text] By using a combination of experimental and computational experiments, we demonstrated that a second-generation dendrigraft of poly-l-lysine neutralizes the anticoagulant activity of unfractionated heparin, low-molecular-weight heparin, and fondaparinux more efficiently than protami...

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Опубликовано в: :ACS Med Chem Lett
Главные авторы: Ourri, Benjamin, Francoia, Jean-Patrick, Monard, Gerald, Gris, Jean-Christophe, Leclaire, Julien, Vial, Laurent
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2019
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580796/
https://ncbi.nlm.nih.gov/pubmed/31223448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00090
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