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Structure of Fission Yeast Transcription Factor Pho7 Bound to pho1 Promoter DNA and Effect of Pho7 Mutations on DNA Binding and Phosphate Homeostasis

Pho7 is the Schizosaccharomyces pombe fission yeast Zn(2)Cys(6) transcriptional factor that drives a response to phosphate starvation in which phosphate acquisition genes are upregulated. Here we report a crystal structure at 1.6-Å resolution of the Pho7 DNA-binding domain (DBD) bound at its target...

詳細記述

保存先:
書誌詳細
出版年:Mol Cell Biol
主要な著者: Garg, Angad, Goldgur, Yehuda, Sanchez, Ana M., Schwer, Beate, Shuman, Stewart
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580706/
https://ncbi.nlm.nih.gov/pubmed/31010807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00132-19
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