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Role of ketone signaling in the hepatic response to fasting

Ketosis is a metabolic adaptation to fasting, nonalcoholic fatty liver disease (NAFLD), and prolonged exercise. β-OH butyrate acts as a transcriptional regulator and at G protein-coupled receptors to modulate cellular signaling pathways in a hormone-like manner. While physiological ketosis is often...

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Опубликовано в: :Am J Physiol Gastrointest Liver Physiol
Главные авторы: Geisler, Caroline E., Ghimire, Susma, Bogan, Randy L., Renquist, Benjamin J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580236/
https://ncbi.nlm.nih.gov/pubmed/30767679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00415.2017
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