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Structural and functional characterization of CMP-N-acetylneuraminate synthetase from Vibrio cholerae

Several pathogenic bacteria utilize sialic acid, including host-derived N-acetylneuraminic acid (Neu5Ac), in at least two ways: they use it as a nutrient source and as a host-evasion strategy by coating themselves with Neu5Ac. Given the significant role of sialic acid in pathogenesis and host-gut co...

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Bibliografske podrobnosti
izdano v:Acta Crystallogr D Struct Biol
Main Authors: Bose, Sucharita, Purkait, Debayan, Joseph, Deepthi, Nayak, Vinod, Subramanian, Ramaswamy
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580227/
https://ncbi.nlm.nih.gov/pubmed/31205019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798319006831
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