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Role of T Cell-To-Dendritic Cell Chemoattraction in T Cell Priming Initiation in the Lymph Node: An Agent-Based Modeling Study

The adaptive immune response is initiated in lymph nodes by contact between antigen-bearing dendritic cells (DCs) and antigen-specific T cells. A selected number of naïve T cells that recognize a specific antigen may proliferate into expanded clones, differentiate, and acquire an effector phenotype....

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Pubblicato in:Front Immunol
Autori principali: Azarov, Ivan, Peskov, Kirill, Helmlinger, Gabriel, Kosinsky, Yuri
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579912/
https://ncbi.nlm.nih.gov/pubmed/31244840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01289
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