Cholesterol-rich lipid-mediated nanoparticles boost of transfection efficiency, utilized for gene editing by CRISPR-Cas9

Purpose: Gene therapy has become a promising remedy to treat disease by modifying the person’s genes. The therapeutic potential of related tools such as CRISPR-Cas9 depends on the efficiency of delivery to the targeted cells. Numerous transfection reagents have been designed and lots of efforts have...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Hosseini, Elaheh Sadat, Nikkhah, Maryam, Hosseinkhani, Saman
Format: Artigo
Language:Inglês
Published: Dove 2019
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579871/
https://ncbi.nlm.nih.gov/pubmed/31354265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S199104
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