Immunoglobulin gene rearrangement IGHV3-48 is a predictive marker of histological transformation into aggressive lymphoma in follicular lymphomas

Follicular lymphoma (FL) is a heterogeneous disease whose pathogenesis remains partially unknown. Around 20% of FL patients experience early progression or treatment-refractory disease and 2–3% of patients per year experience histological transformation (HT) into a more aggressive lymphoma (tFL). He...

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Vydáno v:Blood Cancer J
Hlavní autoři: García-Álvarez, María, Alonso-Álvarez, Sara, Prieto-Conde, Isabel, Jiménez, Cristina, Sarasquete, M. Eugenia, Chillón, M. Carmen, Medina, Alejandro, Balanzategui, Ana, Maldonado, Rebeca, Antón, Alicia, Puig, Noemí, Rodríguez, Marta, Blanco, Oscar, Tamayo, Pilar, González-Calle, Verónica, Martín, Alejandro, García-Sanz, Ramón, González, Marcos, Caballero, M. Dolores, Alcoceba, Miguel
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579759/
https://ncbi.nlm.nih.gov/pubmed/31209206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0213-9
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