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Intratumoral heterogeneity: more than just mutations

Most human tumors are composed of genetically and phenotypically heterogeneous cancer cell populations that poses a major challenge for the clinical management of cancer patients. Advances of single cell technologies have allowed the profiling of tumors at unprecedented depth, which in combination w...

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Publicat a:Trends Cell Biol
Autors principals: Hinohara, Kunihiko, Polyak, Kornelia
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579620/
https://ncbi.nlm.nih.gov/pubmed/30987806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2019.03.003
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