Systemic miRNA Delivery by Nontoxic Nanoscale Coordination Polymers Limits Epithelial-to-Mesenchymal Transition and Suppresses Liver Metastases of Colorectal Cancer

Though early detection and treatment of primary tumors has significantly improved in recent years, metastatic disease remains among the most significant challenges in cancer therapy. Cancer cells can disseminate before the primary tumor is detected to form micro or gross metastases, requiring toxic...

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Publicat a:Biomaterials
Autors principals: Chan, Christina, Guo, Nining, Duan, Xiaopin, Han, Wenbo, Xue, Lai, Bryan, Darren, Wightman, Sean C., Khodarev, Nikolai N., Weichselbaum, Ralph R., Lin, Wenbin
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579118/
https://ncbi.nlm.nih.gov/pubmed/31060867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.04.028
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