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The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies

Nova-1, a protein expressed in tumors and neurons, is a target antigen in a human paraneoplastic motor disorder [paraneoplastic opsoclonus- myoclonus ataxia (POMA)]. We evaluated the relationship between the function of Nova-1 and its role as a disease antigen. We show that Nova- 1 is a neuron-speci...

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Pubblicato in:J Neurosci
Autori principali: Buckanovich, RJ, Yang, YY, Darnell, RB
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578795/
https://ncbi.nlm.nih.gov/pubmed/8558240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-03-01114.1996
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