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Beta subunit coexpression and the alpha1 subunit domain I-II linker affect piperidine block of neuronal calcium channels
The effects of local anesthetics were examined on a family of transiently expressed neuronal calcium channels. Fomocaine, a local anesthetic containing a morpholine ring, preferentially blocked alpha1E channels (Ki = 100 microM), and had a lower affinity (3- to 15-fold) for alpha1A, alpha1B, and alp...
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| Gepubliceerd in: | J Neurosci |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Society for Neuroscience
1996
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6578750/ https://ncbi.nlm.nih.gov/pubmed/8786420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-08-02430.1996 |
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