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AMPA receptor activation is rapidly toxic to cortical astrocytes when desensitization is blocked

Although cultured astrocytes express functional glutamate receptors, they are generally resistant to excitotoxic cell death. We explored the role of receptor desensitization in glutamate-mediated astrocyte injury. In cultures of type 1 astrocytes from mouse neocortex, brief application of AMPA evoke...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: David, JC, Yamada, KA, Bagwe, MR, Goldberg, MP
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578741/
https://ncbi.nlm.nih.gov/pubmed/8613786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-01-00200.1996
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