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DNA damage and apoptosis in Alzheimer's disease: colocalization with c- Jun immunoreactivity, relationship to brain area, and effect of postmortem delay

Many neurons in Alzheimer's disease (AD) exhibit terminal deoxynucleotidyl transferase (TdT) labeling for DNA strand breaks with a distribution suggestive of apoptosis. We have shown previously that immunoreactivity for c-Jun is elevated in AD and found in association with neuronal pathology. I...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Anderson, AJ, Su, JH, Cotman, CW
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578676/
https://ncbi.nlm.nih.gov/pubmed/8774439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-05-01710.1996
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