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Lesion-induced sprouting of commissural/associational axons and induction of GAP-43 mRNA in hilar and CA3 pyramidal neurons in the hippocampus are diminished in aged rats

Removal of synaptic connections following a partial deafferentation lesion results in a sprouting of remaining afferents that terminate near the denervated area. However, while the ability to form new synapses in response to injury has been reported in both young and aged rats, previous studies have...

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Pubblicato in:J Neurosci
Autori principali: Schauwecker, PE, Cheng, HW, Serquinia, RM, Mori, N, McNeill, TH
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578136/
https://ncbi.nlm.nih.gov/pubmed/7891181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-03-02462.1995
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