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A single histidine residue is essential for zinc inhibition of GABA rho 1 receptors

The GABA rho 1 subunit, cloned from a human retina library, can form homooligomeric receptors with properties similar to GABAc receptors characterized in retinal cells. The divalent cation Zn2+, abundant in the CNS and retina, was found to inhibit GABA rho 1 receptors in a voltage-independent manner...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Wang, TL, Hackam, A, Guggino, WB, Cutting, GR
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 1995
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578093/
https://ncbi.nlm.nih.gov/pubmed/7472519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-11-07684.1995
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