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Persistent activation of cAMP-dependent protein kinase by regulated proteolysis suggests a neuron-specific function of the ubiquitin system in Aplysia

In response to the facilitating neurotransmitter serotonin (5-HT), the cAMP-dependent protein kinase (PKA) acquires a special mnemonic characteristic in Aplysia sensory neurons. PKA becomes persistently activated at basal cAMP concentrations owing to a decreased regulatory (R) to catalytic (C) subun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Chain, DG, Hegde, AN, Yamamoto, N, Liu-Marsh, B, Schwartz, JH
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578082/
https://ncbi.nlm.nih.gov/pubmed/7472510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-11-07592.1995
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