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A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells

We describe a timetable of events during programmed cell death (PCD) in neuronal PC12 cells, specifically, Ras signaling, immediate-early gene (IEG) expression, DNA fragmentation and commitment to PCD. Commitment occurs over a period from 10–20 hr after NGF withdrawal. Ras signaling declines rapidly...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Mesner, PW, Epting, CL, Hegarty, JL, Green, SH
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578068/
https://ncbi.nlm.nih.gov/pubmed/7472489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-11-07357.1995
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