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Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity

We have developed “pure” neuronal cultures (< 1% astrocytes) from mouse neocortex to study the effect of glial cells on the response of neurons to injury. Cortical neurons were found to require glial-conditioned medium to survive. Immature neurons, 2–4 d in vitro, deprived of glial- conditioned m...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Dugan, LL, Bruno, VM, Amagasu, SM, Giffard, RG
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577706/
https://ncbi.nlm.nih.gov/pubmed/7540679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-06-04545.1995
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