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Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor

The immunotoxin 192 IgG-saporin, produced by coupling the ribosome- inactivating protein saporin to the monoclonal 192 IgG antibody against the low-affinity p75 NGF receptor (NGFr), was injected into the cerebral ventricle, septal area, and substantia innominata of adult rats. Injections into the ce...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Heckers, S, Ohtake, T, Wiley, RG, Lappi, DA, Geula, C, Mesulam, MM
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1994
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577567/
https://ncbi.nlm.nih.gov/pubmed/8120624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.14-03-01271.1994
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