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Effects of intrahypothalamic administration of antisense DNA for progesterone receptor mRNA on reproductive behavior and progesterone receptor immunoreactivity in female rat

Since reproductive behaviors of female rats can be correlated with estrogen-induced increases in progestin binding by hypothalamic neurons, we hypothesized that specific progesterone receptor (PR) antisense DNA sequences might decrease these behaviors. Antisense oligonucleotides (15 bases), spanning...

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Publicat a:J Neurosci
Autors principals: Ogawa, S, Olazabal, UE, Parhar, IS, Pfaff, DW
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577563/
https://ncbi.nlm.nih.gov/pubmed/8126569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.14-03-01766.1994
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