Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease

We have examined several aspects of neurotransmitter function in the brains of mice carrying a deletion mutation in the gene encoding the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT). During the first 6 weeks of postnatal development, dopamine levels in whole-brain ext...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Jinnah, HA, Wojcik, BE, Hunt, M, Narang, N, Lee, KY, Goldstein, M, Wamsley, JK, Langlais, PJ, Friedmann, T
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1994
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577527/
https://ncbi.nlm.nih.gov/pubmed/7509865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.14-03-01164.1994
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