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Kappa 2 opioid receptors inhibit NMDA receptor-mediated synaptic currents in guinea pig CA3 pyramidal cells

The role of the endogenous opioid peptide dynorphin (1–17) in regulating NMDA receptor-mediated synaptic currents was examined in guinea pig hippocampus. Schaffer collateral/commissural fiber-evoked NMDA synaptic currents were recorded using whole-cell patch-clamp techniques in CA3 pyramidal cells....

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Publicat a:J Neurosci
Autors principals: Caudle, RM, Chavkin, C, Dubner, R
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6577080/
https://ncbi.nlm.nih.gov/pubmed/7916046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.14-09-05580.1994
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