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Integrating genome-wide association and eQTLs studies identifies the genes associated with age at menarche and age at natural menopause

OBJECTIVE: An early onset of menarche and, later, menopause are well-established risk factors for the development of breast cancer and endometrial cancer. Although the largest GWASs have identified 389 independent signals for age at menarche (AAM) and 44 regions for age at menopause (ANM), GWAS can...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wang, Gang, Lv, Jian, Qiu, Xiaoxin, An, Yujun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576755/
https://ncbi.nlm.nih.gov/pubmed/31206546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213953
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