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Integrating genome-wide association and eQTLs studies identifies the genes associated with age at menarche and age at natural menopause

OBJECTIVE: An early onset of menarche and, later, menopause are well-established risk factors for the development of breast cancer and endometrial cancer. Although the largest GWASs have identified 389 independent signals for age at menarche (AAM) and 44 regions for age at menopause (ANM), GWAS can...

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Pubblicato in:PLoS One
Autori principali: Wang, Gang, Lv, Jian, Qiu, Xiaoxin, An, Yujun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576755/
https://ncbi.nlm.nih.gov/pubmed/31206546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213953
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