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GM1 ganglioside improves dopaminergic markers of rat mesencephalic cultures treated with MPP+

Rat embryonic mesencephalic cultures were employed to evaluate the consequences of adding GM1 ganglioside to cultures lesioned with the selective neurotoxin 1-methyl-4-phenylpyridinium (MPP+). MPP+ reduced dopamine and DOPAC content, dopamine uptake, aromatic L-amino acid decarboxylase activity, and...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Dalia, A, Neff, NH, Hadjiconstantinou, M
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576684/
https://ncbi.nlm.nih.gov/pubmed/8101212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.13-07-03104.1993
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