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Involvement of a metalloprotease in low-affinity nerve growth factor receptor truncation: inhibition of truncation in vitro and in vivo

The mechanism of low-affinity NGF receptor (LNGFR) truncation was investigated in cultured Schwann cells. Affinity labeling of Schwann cells with 125I-NGF or metabolic labeling with 35S-cysteine showed that truncated NGF receptor (NGF-Rt) was derived from the cell surface form of the receptor. Addit...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: DiStefano, PS, Chelsea, DM, Schick, CM, McKelvy, JF
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576503/
https://ncbi.nlm.nih.gov/pubmed/8501514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.13-06-02405.1993
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