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Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents

A distinctive characteristic of the AMPA subset of glutamate receptor channels is their remarkably rapid desensitization. A family of compounds, the benzothiadiazides, is described here that potently inhibit rapid glutamate receptor desensitization. The structure- activity relationships of these com...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Yamada, KA, Tang, CM
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576449/
https://ncbi.nlm.nih.gov/pubmed/8103555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.13-09-03904.1993
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