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Decreased rates of cerebral protein synthesis measured in vivo in a mouse model of Tuberous Sclerosis Complex: unexpected consequences of reduced tuberin

Tuberous Sclerosis Complex (TSC) is an autosomal dominant neurogenetic disorder affecting about 1 in 6,000 people and caused by mutations in either TSC1 or TSC2. This disorder is characterized by increased activity of mammalian target of rapamycin complex 1 (mTORC1), which is involved in regulating...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Saré, R. Michelle, Huang, Tianjian, Burlin, Tom, Loutaev, Inna, Smith, Carolyn Beebe
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576257/
https://ncbi.nlm.nih.gov/pubmed/29364507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14311
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