Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRVδ1 and TCRVδ2 γδ T lymphocytes

γδ T lymphocytes represent ∼1% of human peripheral blood mononuclear cells and even more cells in most tissues of vertebrates. Although they have important anticancer functions, most current single-cell RNA sequencing (scRNA-seq) studies do not identify γδ T lymphocytes because their transcriptomes...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pizzolato, Gabriele, Kaminski, Hannah, Tosolini, Marie, Franchini, Don-Marc, Pont, Fréderic, Martins, Fréderic, Valle, Carine, Labourdette, Delphine, Cadot, Sarah, Quillet-Mary, Anne, Poupot, Mary, Laurent, Camille, Ysebaert, Loic, Meraviglia, Serena, Dieli, Francesco, Merville, Pierre, Milpied, Pierre, Déchanet-Merville, Julie, Fournié, Jean-Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576116/
https://ncbi.nlm.nih.gov/pubmed/31118283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818488116
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