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The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain

The beta-adrenergic receptor kinase (beta ARK) phosphorylates the agonist-occupied beta-adrenergic receptor to promote rapid receptor uncoupling from Gs, thereby attenuating adenylyl cyclase activity. Beta ARK-mediated receptor desensitization may reflect a general molecular mechanism operative on m...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Arriza, JL, Dawson, TM, Simerly, RB, Martin, LJ, Caron, MG, Snyder, SH, Lefkowitz, RJ
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1992
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575981/
https://ncbi.nlm.nih.gov/pubmed/1403099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-10-04045.1992
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