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Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro

In ischemic and in inflamed tissues, pH levels down to 5.4 have been measured, and this local acidosis may contribute to pain and hyperalgesia in disease states. To evaluate the role of acid pH in nociception, we have studied identified primary afferents in a rat skin- saphenous nerve preparation in...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Steen, KH, Reeh, PW, Anton, F, Handwerker, HO
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575698/
https://ncbi.nlm.nih.gov/pubmed/1309578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-01-00086.1992
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